| 产品名 | 产品编码 | 分子库数量 | 产品包装 （DMSO溶液/10mM） |
| 免疫活性化合物库Target Probe+ | LA-1008 | 免疫化合物分子75个 M 系列131个 C系列167个 |
96孔板： 10 μL/well, 20 μL/well, 或100 μL/well |
“免疫”是人体极其重要的自卫功能。人体依靠自身的免疫力，能抵御种类庞大的的各种疾病。天然产物中多种活性物质具有免疫活性，如多酚类、黄酮类、含氮杂环类化合物等。
该库收集了75个免疫类化合物，对其进行M+C系列改造成潜在的新的活性分子（已改造～300个），可以广泛地应用于高通量筛选 (HTS) 和高内涵筛选 (HCS)，为优化药物结构提供了重要的线索；同时继续提供定制的P系列分子。
图1 免疫类活性化合物已知相关疾病领域
表2 免疫类活性化合物已知药物靶点示例
| Xanthine dehydrogenase | Carbonic anhydrase | Cytochrome P450 1B1/1A2/1A1/19A1 | Arachidonate 5-lipoxygenase |
| Microtubule-associated protein tau | Aldehyde dehydrogenase | Estrogen receptor alpha/beta | Muscleblind-like protein 1/2/3 |
| 5-hydroxytryptamine receptor 1A/1B/2A/2B/2C (by homology) | Beta amyloid A4 protein | Tyrosyl-DNA phosphodiesterase 1 | Androgen receptor |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Glucocorticoid receptor | Epidermis-type lipoxygenase 3 (by homology) | ATP-binding cassette sub-family G member 2 |
| P-glycoprotein 1 | Vascular endothelial growth factor receptor 1/2/3 (by homology) | Platelet-derived growth factor receptor alpha/beta | Adenosine receptor A1 (by homology) |
| Fibroblast growth factor receptor 1/2/3/4 | Caspase-3 subunit p12 | Caspase-7 subunit p20 (by homology) | Caspase-6 subunit p18 (by homology) |
| Neutrophil elastase | Azurocidin (by homology) | Myeloblastin (by homology) | Quinone oxidoreductase (by homology) |
| Mitogen-activated protein kinase 8/9/10 (by homology) | Mineralocorticoid receptor (by homology) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (by homology) |
| Arachidonate 15-lipoxygenase B | |||
| 绿色：与原天然产物的靶点相同；黑色：新靶点 | |||
