| 产品名 | 产品编码 | 分子库数量 | 产品包装 （DMSO溶液/10mM） |
| 抗衰老活性化合物库Target Probe+ | LA-1009 | 活性分子118个 M 系列230个 C系列274个 |
96孔板： 10 μL/well, 20 μL/well, 或100 μL/well |
衰老是一个复杂的生物过程，多种慢性疾病，如癌症、糖尿病、阿尔茨海默病等都会导致组织器官功能衰退、结构退化、适应能力和抵抗力降低等与衰老相关的问题。
该库收集了118个抗衰老类化合物，对其进行M+C系列改造成潜在的新的活性分子（已改造得到～600个），可以广泛地应用于高通量筛选 (HTS) 和高内涵筛选 (HCS)，为优化药物结构提供了重要的线索；同时继续提供定制的P系列分子。
图 1 抗衰老活性化合物已知相关疾病领域
表2 抗衰老活性化合物药物靶点示例
| Dopamine D2 receptor (by homology) | Dopamine transporter (by homology) | Carbonic anhydrase | Alpha-(1,3)-fucosyltransferase 7 |
| Squalene monooxygenase (by homology) | ATP-binding cassette sub-family G member 2 | NADPH oxidase 4 | Plasminogen |
| Xanthine dehydrogenase | Cytochrome P450 1B1 | Cytochrome P450 19A1 | Cytochrome P450 2C9 |
| Cytochrome P450 3A4 | Cytochrome P450 2C19 | NADPH oxidase 4 | Glucocorticoid receptor |
| Leukocyte elastase | Aldose reductase (by homology) | Cyclooxygenase-2 | Cyclooxygenase-1 |
| Adenosine A3 receptor | Adenosine A1 receptor (by homology) | Transthyretin | Arachidonate 5-lipoxygenase |
| Arachidonate 15-lipoxygenase | Arachidonate 12-lipoxygenase | Receptor-type tyrosine-protein phosphatase S | Serotonin 1a (5-HT1a) receptor |
| Arachidonate 15-lipoxygenase | Transthyretin | Glucocorticoid receptor | Insulin-like growth factor I receptor |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Phosphodiesterase 5A | Tyrosine-protein kinase receptor FLT3 | Nitric oxide synthase, inducible (by homology) |
| Dual specificity mitogen-activated protein kinase kinase 1 | Multidrug resistance-associated protein 1 | P-glycoprotein 1 | Aldehyde dehydrogenase |
| Estradiol 17-beta-dehydrogenase 2 | Carbonyl reductase [NADPH] 1 | Beta-secretase 1 | Beta amyloid A4 protein |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Delta opioid receptor | Taste receptor type 2 member 31 | Estrogen receptor alpha |
| Quinone reductase 2 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | Cannabinoid receptor 2 | Melatonin receptor 1A |
| Melatonin receptor 1B |
