| 产品名 | 产品编码 | 产品包装 （DMSO溶液/10mM） |
| 抗癌活性化合物库Target Probe+ | LA-1006 | 96孔板： 10 μL/well, 20 μL/well, 或100 μL/well |
癌症是目前直接危及人类生命最常见也是最严重的疾病之一，据不完全统计,全世界每年有近2000万人新患癌症,又有1000万左右的人因癌症去世,占死亡人口总数的1/4左右,这个数字还处于飞速的增长中。
癌症是世界医学界久攻不下的顽疾，原因之一是因为现代医学界至今对癌症的病因还没有真正了解。该化合物库分子可以广泛地应用于高通量筛选 (HTS) 和高内涵筛选 (HCS)，为优化药物结构提供了重要的线索；同时继续提供定制的P系列分子，可用于精确的蛋白质谱研究和发现药物在各种细胞内，包括人类活细胞，与各类蛋白靶点结合的情况，用于深入的研究药物作用机理和药物改造。
图1 抗癌类活性化合物已知相关疾病领域
表2 抗癌类活性化合物已知药物靶点示例
| Microtubule-associated protein tau | Carbonic anhydrase II/VII/XII/IV | Tyrosyl-DNA phosphodiesterase 1 | Estrogen receptor alpha |
| Xanthine dehydrogenase | Arachidonate 15-lipoxygenase B/ Arachidonate 5-lipoxygenase | Adenosine receptor A1/A3 (by homology) | Cytochrome P450 1B1/1A2/1A1/19A1 |
| Aldo-keto reductase family 1 member B10 (by homology) | Androgen receptor | P-glycoprotein 1 | ATP-binding cassette sub-family G member 2 |
| Epidermis-type lipoxygenase 3 (by homology) | Aldehyde dehydrogenase | Vascular endothelial growth factor receptor 1/2/3 (by homology) | Muscleblind-like protein 1/2/3 |
| 5-hydroxytryptamine receptor 2A/2B/2C (by homology) | Beta amyloid A4 protein | Platelet-derived growth factor receptor alpha/beta | Fibroblast growth factor receptor 1/2/3/4 |
| Caspase-3 subunit p12/p20/p18 | Neutrophil elastase | Azurocidin (by homology) | Myeloblastin (by homology) |
| Quinone oxidoreductase (by homology) | Mitogen-activated protein kinase 8/9/10 (by homology) | cGMP-specific 3',5'-cyclic phosphodiesterase | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (by homology) |
| Glucocorticoid receptor | Mineralocorticoid receptor (by homology) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | |
| 绿色：与原天然产物的靶点相同；黑色：新靶点 | |||
